Type and function — what this transceiver does
The DS8921ATM/NOPB is a full-duplex transceiver supporting both RS-422 and RS-485 protocols.
Supply voltage and 3.3V compatibility
It is not designed for 3.3V logic — the receiver hysteresis of 70 mV is specified at 5V nominal. If your system runs on a 3.3V bus, you will need a level translator or a different transceiver rated for that supply.