48 MHz Cortex-M0 — enough for sensor fusion and UI
The CY8C4245AXI-483: At 48 MHz, the Cortex-M0 handles real-time tasks like reading the ADC, updating a PWM period, and scanning a CapSense matrix in the same loop. The 4 KB SRAM is tight for heavy buffering, but the part is designed for control-oriented applications where the data stays in registers or Flash lookup tables. If you need Bluetooth or more memory, the CY8C4247LQI-BL473 adds BLE and a larger Flash bank, but for a wired HMI or sensor node this is the right density tier.
Sourcing this part for your BOM line
For a BOM freeze, the active lifecycle means no imminent LTB, but dual-sourcing with the CY8C4245LQI-483 (same core, same peripherals, 34 I/O in a QFN) gives supply resilience if the TQFP variant tightens.