Cortex-M4F with FPU in a 1.8 V core — the mixed-signal workhorse
That ADC count — 37 total channels — makes this part a signal-chain MCU for applications that need to digitise multiple sensor inputs without external multiplexers or separate ADCs.
64-LQFP — rework-friendly, but watch the 1.8 V plane
The 64-LQFP (10x10 mm) is a standard fine-pitch package that reflows cleanly with a typical leaded profile. The exposed paddle is not present on this package — all dissipation goes through the leads, so thermal budget is limited. The 1.65 V to 1.95 V supply on the VDD pins means the decoupling caps should be 100 nF per pin pair plus a bulk 4.7 µF or 10 µF on the 1.8 V plane; do not share this rail with a 3.3 V peripheral supply without a level translator.
51 I/O and CANbus — industrial and automotive-adjacent connectivity
The HDMI-CEC interface is a niche addition useful for consumer AV equipment.
ST lists the STM32F378RCT6 as Active. The base product number STM32F378 sits in the STM32F3 series, which remains a current portfolio line. The 64-LQFP package is a common footprint across several STM32F3 density variants, so a pin-compatible drop-in to a higher Flash or RAM sibling is possible without a board spin if the firmware scales.