The I²C isolator that does not force you to redesign the bus
The ADUM2251ARIZ-RL is an Analog Devices iCoupler magnetic-coupling digital isolator built specifically for I²C buses. It integrates direction control internally — Side 1 has two bidirectional channels (SDA, SCL) and Side 2 has one unidirectional output. That 2/1 input count matches the standard I²C isolator topology. The 5000Vrms isolation rating is reinforced-grade. Data rate is 1Mbps.
The 5000Vrms isolation voltage drives the creepage and clearance distances on the PCB. The common-mode transient immunity is 25kV/µs minimum, so this part holds up in motor-drive or inverter environments where fast-switching SiC or IGBT stages slam the bus with common-mode edges. No isolated power on-chip — you still need a separate isolated DC-DC or a third-party isolated supply for the secondary side if the bus is referenced to a different ground.
Temperature range and field life
The supply voltage range is 3V to 5.5V, so it runs on either a 3.3V or 5V I²C rail without a level-shifter — handy when the master is 3.3V and a sensor on the isolated side is 5V. Pulse-width distortion is 145ns max on the bidirectional channels and 85ns max on the unidirectional channel — tight enough to avoid bit errors at 1Mbps, but if you are running a long bus with many slaves, budget that skew into the timing.