Input mux: six differential or twelve single-ended
The mux gives you a choice: six differential pairs for signals that need common-mode rejection (bridge sensors, thermocouples with long leads), or twelve single-ended channels when every input shares a common ground. The differential mode is the better pick when your sensor ground is a few hundred millivolts away from the ADC ground — the SAR core sees the difference, not the offset. Single-ended mode doubles channel count at the cost of sharing the return path. Both modes feed the same 10-bit SAR core, so resolution stays 10 bits regardless of configuration.
I²C bus and 5V-only supply
The digital interface is I²C, so it needs only two wires (SCL, SDA) plus the 5V rail and ground. No parallel bus, no SPI chip-select — just a device address and a start condition.
Lifecycle and sourcing posture
That means it is a safe choice for a new BOM line or a production sustainment contract. It is also ROHS3 compliant, so it passes the EU material restrictions without an exemption.